Windows is the default for most label printers. Macs are usually fine; Chromebooks are where buyers get stuck. This guide separates documented support from workarounds.
Mac: three kinds of support
AirPrint over Wi-Fi. No driver install. Rollo documents AirPrint certification for its Wi-Fi printer; Brother references AirPrint for the QL-1110NWB and QL-820NWB.
Maker-supplied macOS driver. Rollo USB (Mac 10.9+), Phomemo 241BT (macOS 10.9+), MUNBYN, iDPRT, POLONO and Arkscan list macOS. DYMO requires macOS 14 or later for the 5XL with DYMO Connect.
Generic CUPS setup. Zebra's desktop printers are normally set up on a Mac with a CUPS driver rather than a Zebra-packaged macOS installer. We mark those Mac entries Conditional.
Chromebook: why it's harder
Chromebooks can't run the Windows or macOS driver installers many label printers depend on. So "works with Chromebook" should mean the maker documents a ChromeOS method. In our catalog:
Printer
ChromeOS status
How
Rollo Wireless
Confirmed
Network printing over Wi-Fi
iDPRT SP410
Confirmed
iDPRT lists "Chrome"; setup steps aren't on the product page
Arkscan 2054A-LAN
Conditional
Listed by Arkscan; network (LAN) connection
MUNBYN RW403B
Conditional
Browser-based Munbyn Editor, not a system driver
MUNBYN P941U
Conditional
MUNBYN lists Chromebook for the 941 series; confirm the USB method
If you use a Mac only, most printers work; prefer AirPrint if you'd rather not install drivers. If you use a Chromebook, choose a printer with a Confirmed ChromeOS status and read its review's setup notes.